Clinical Papers

For over two decades the leaders and scientists behind InMode have been revolutionizing the medical aesthetic industry with state-of-the-art technologies. InMode now has over 35+ peer reviewed / textbook publications proving to be a leader in clinical excellence. Read and browse through our numerous studies.

Clinical papers

Clinical paper search

Improving Outcomes in Upper Arm Liposuction: Adding Radiofrequency-Assisted Liposuction to Induce Skin Contraction

Background: Brachioplasty is frequently recommended for patients with more skin laxity than subcutaneous fat. However, many patients are reluctant to accept a visible scar that will affect the activity of the upper arm or clothing choices. Traditional liposuction is effective when minimal skin laxity is present, but the dual problems of postoperative residual skin laxity and unsatisfactory contour irregularities are common when upper arm skin laxity is the chief complaint.

Objectives: The author investigates the degree of skin contraction resulting from treatment with radiofrequency-assisted liposuction (RFAL) and attempts to determine whether, after long-term follow-up, the classification of upper arm deformities and their corresponding treatment protocols can be refined to offer patients with prominent skin laxity an alternative to traditional brachioplasty.

Results: One year after treatment with RFAL, the mean surface area reduction in the volar upper arm region was 33.5% bilaterally. The mean degree of pendulous vertical “hang” shortening was 50%bilaterally. Statistical analysis showed a P value of >.001 for both measurements.

Conclusion: Treatment with RFAL achieved statistically significant skin contraction in the upper arm region. Patients in categories 2b and 4 were successfully treated with RFAL instead of traditional brachioplasty (which is recommended by the current classification system). Category 3 patients, however, did require a short-scar brachioplasty procedure to obtain satisfactory results.

Author: D. Duncan

Technology: FaceTite BodyTite

Published Date: 8/19/2016

Publication: Aesthetic Surgery Journal

Non-Excisional Face and Neck Tightening Using a Novel Subdermal Radiofrequency Thermo-Coaugulative Device


42 patients with broad age and ethnic demographics where treated with a novel, non-excisional, minimally invasive device to coagulate a very thin layer of sub-dermal septo-fascial fat, denature the deep reticular dermis and tighten the skin and sub-dermal matrix of connective tissue. The detailed treatment protocol and results are presented. Patients were observed for up to 6 month following the procedure. No major side effects were observed. The aesthetic outcome of this non-excisional procedure includes improvement of the position and shape of the cheek, lower lid-cheek junction, jawline and neck. The overall aesthetic results deliver a noticeable and impressive tightening of the soft-tissue and may be compared with a conservative, small excisional procedure. The authors propose this versatile device and treatment as a non-excisional, moderate facial rejuvenation procedure on its own, or as an adjunct to open procedures performed simultaneously, or as a simplified treatment for secondary skin laxity in combination with a lift procedure.

Author: D. Ahn, R. Mulholland, D. Duncan, M. Paul

Technology: FaceTite BodyTite

Published Date: 8/19/2016

Publication: Journal of Cosmetics, Dermatological Sciences and Applications

A New Approach for Adipose Tissue Treatment and Body Contouring Using RFAL

“Radiofrequency-assisted liposuction is a promising technology for body contouring with the following apparent advantages:

  • Ability to heat a significant volume of tissue quickly and uniformly
  • Ability to control tissue heating through direct monitoring of temperature and tissue impedance.
  • Defragmentation of fat cells and coagulation of blood vessels in the treated zone, reducing bleeding and bruising
  • Obvious collagen denaturation after RFAL treatment
  • Significant contraction and retraction of adipose and dermal tissue after treatment.”

A new liposuction technology for adipocyte lipolysis and uniform three-dimensional tissue heating and contraction is presented. The technology is based on bipolar radiofrequency energy applied to the subcutaneous adipose tissue and subdermal skin surface. Preliminary clinical results, thermal monitoring, and histologic biopsies of the treated tissue demonstrate rapid preaspiration liquefaction of adipose tissue, coagulation of subcutaneous blood vessels, and uniform sustained heating of tissue.

Author: M. Paul, S. Mulholland

Technology: FaceTite BodyTite

Published Date: 8/19/2016

Publication: Aesthetic Plastic Surgery Journal

A Safety and Feasibility Study of a Novel Radiofrequency-Assisted Liposuction Technique

“Body contour improvement was observed postoperatively in all patients and there were no severe systemic or local complications, although postoperative pain was minimal in all patients. Weight and circumference reductions were significant at both 6-week and 3-month follow-up. Skin tightening was judged optimal by the surgeon in all patients. “


Background: The feasibility, safety, and efficacy of a novel radiofrequency device for radiofrequency-assisted liposuction were evaluated in various body areas.

Methods: From July to December of 2008, 23 subjects underwent radiofrequency-assisted liposuction using the BodyTite system. Information regarding aesthetic results and local and systemic complications was collected immediately after the procedure and at 6- and 12-week follow-up.

Results: The mean age of the patients was 38.8 ± 12.4 years, and 87 percent were women. Radiofrequency-assisted liposuction was performed successfully in all cases; volume aspirated per patient was 2404 ± 1290 ml, whereas operative time was 158 ± 44 minutes. All patients underwent liposuction at the hip and low abdominal areas, laterally. Body contour improvement was observed postoperatively in all patients and there were no severe systemic or local complications, although postoperative pain was minimal in all
patients. Weight and circumference reductions were significant at both 6-week and 3-month follow-up. Skin tightening was judged optimal by the surgeon in all patients.

Conclusions: The authors’ study suggests that the removal of moderate volumes of fat with concurrent subdermal tissue contraction can be performed safely and effectively with radiofrequency-assisted liposuction. Additional benefits of this technique are excellent patient tolerance and fast recovery time. Nonetheless, a larger sample is required to confirm the authors’ results and guarantee the efficacy and safety of the procedure. Direct comparison with traditional liposuction or energy-assisted liposuction techniques may provide some insights to tailor future indications of this novel technique.

Author: G. Blugerman, D. Schalvezon, M. Paul

Technology: FaceTite BodyTite

Published Date: 8/19/2016

Publication: Plastic and Reconstructive Surgery

Gynecomastia Treatment Using Radiofrequency-Assisted Liposuction (RFAL)

Background: Male gynecomastia is a commonly occurring aesthetic concern. Traditional liposuction, laser and ultrasound-assisted liposuction have many limitations, and excisional gynecomastia procedures can leave undesirable scars in the treatment of the enlarged male breast.

Methods: In this study, the authors report the use of radiofrequency-assisted liposuction (RFAL) in the treatmentof male gynecomastia. A total of 59 males had their gynecomastia treated by RFAL technology, 47/59 by closed RFAL alone, and an additional 12 patients with RFAL combined with our personal technique of trans-mammillary glandular reduction. The RFAL device afforded strong RF current and thermal energy for glandular and adipose coagulation and liquefaction, together with strong soft tissue contraction forces.

Results: All patients were followed for more than 12 months, and all reported good to excellent breast contour results. There was one seroma and over 90 % of patients report being very happy with their contour, and no secondary surgical procedures were necessary. The authors report RFAL as new and potentially powerful option in the treatment of male gynecomastia, having the advantages of strong coagulation, liquefaction and aspiration of glandular tissue, simultaneous coagulation and aspiration with constant thermal monitoring, and very strong soft tissue contraction, eliminating the need for skin resection in the majority of cases. In minority of cases where there may be remnant glandular structures following RFAL, a simple, minimally intrusive trans-mammillary glandular extraction technique can be deployed that leaves minimal scarring.

Conclusions: The mixed technique presented in this study appears to be safe and effective. The RFAL mixed technique has proven to be superior to ultrasonic and power-assisted liposuction due to the skin contraction, having no limitation dependent on the quality of the patient’s skin.

Author: G. Blugerman, D. Schalvezon, S. Mulholland, J. A. Soto, M. Siguen

Technology: FaceTite BodyTite

Published Date: 8/19/2016

Publication: European Journal of Plastic Surgery

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